
14717 items found.
Studies in L2 pragmatic acquisition
This special research seminar examines how second languages (L2) are used in contexts, To be specific, we will survey how learners use L2 in speech acts, storytelling, discourse and conversation activities. In so doing, we will consider learners' first language, proficiency level and learning environment as possible factors influencing their performances.
The course will run mainly in Japanese, but we will read articles in English and Japanese, so students should have some knowledge of English to be able to read the assigned articles. The seminar will be open to both Japanese and foreign students, at graduate or undergraduate level, ideally those with some background in the conduct of research. It would also be beneficial for them to have some understanding of the theories of second language acquisition (SLA). We will have guest speakers' lectures during this summer seminar.
Prior to the start of the seminar, each participant should prepare themselves by reading all the assigned articles. We will assign readings to the participants of the seminar a week prior to the start of the seminar, and they are expected to read and critique those studies well enough to lead the discussion.
As a final project, students will design a study and undertake preliminary efforts to identify relevant background literature and pilot possible instruments that could be used in the collection of data. They will present the above on the last day of the seminar.
Engineering polyketide synthases to produce commodity chemicals.
PKS (Polyketide Synthase) is a large enzyme that contains multiple domains. We design PKSs to produce target compounds by mutating specific residues.
Modeling and simulation of biological systems
One of the most important characteristics of life is that it is active and continues to be active. By acting, living systems interact with the environment and maintain their own existence in the environment. In this project, we will use computer simulations to explore the dynamic behavior of living systems and to understand their operating principles.
Screening for genes determining the sensitivity to anticancer drugs using open database
Students will learn how to use the cancer cell line database (CellMinerCDB, TCGA, depmap, cbioportal, NLC mapper, NCBI, Human Protein Atlas, clinicaltrial.gov and others). Through these analyses, students will learn how anti-cancer agents act, and about DNA repair.
※CellMinerCDB enables exploration and analysis of cancer cell line pharmacogenomic data across different sources.
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CellMinerCDB: https://discover.nci.nih.gov/rsconnect/cellminercdb/
CellMinerCDB enables exploration and analysis of cancer cell line pharmacogenomic data across different sources.
TCGA (The Cancer Genome Atlas): https://portal.gdc.cancer.gov
Database of cancer tissue analyses and the patient prognosis.
Depmap: https://depmap.org/portal/
The analysis tool of cancer cell line pharmacogenomic data across different sources. The essentiality of each gene is validated by gene knockdown or gene knockout.
cBioportal: https://www.cbioportal.org
The cBioPortal for Cancer Genomics is an open-access, open-source resource for interactive exploration of multidimensional cancer genomics data sets. The goal of cBioPortal is to significantly lower the barriers between complex genomic data and cancer researchers by providing rapid, intuitive, and high-quality access to molecular profiles and clinical attributes from large-scale cancer genomics projects, and therefore to empower researchers to translate these rich data sets into biologic insights and clinical applications.
NLC mapper: https://nls-mapper.iab.keio.ac.jp/cgi-bin/NLS_Mapper_form.cgi
Nuclear location signal analysis tool developed by a Kieo IAB team.
NCBI: https://www.ncbi.nlm.nih.gov
The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information.
Human Protein Atlas: https://www.proteinatlas.org
The Human Protein Atlas is a Swedish-based program initiated in 2003 with the aim to map all the human proteins in cells, tissues, and organs using an integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology. All the data in the knowledge resource is open access to allow scientists both in academia and industry to freely access the data for exploration of the human proteome.
The Human Protein Atlas consists of ten separate sections, each focusing on a particular aspect of the genome-wide analysis of the human proteins.
clincaltrials.gov: https://www.clinicaltrials.gov
ClinicalTrials.gov is a database of privately and publicly funded clinical studies conducted around the world.
Circular Fabrication with large-scale 3D Printing
Creating large-Scale metamaterials with 3D-Printing. And discover all the contexts for it, and write a paper for 4D and Functional Fabrication Conference, 2022.10
Fundamental Computer Science
This lecture aims at mastering the basics of computer science. These fundamentals are not rudimentary. The assumed basic contents include CPU architecture, operating systems, networks, distributed systems, transaction processing, reinforcement learning, and machine learning (PRML equivalent).
Analysis of radar observation data
Recently the number of severe disasters by heavy precipitation is increasing. For disaster prevention, accurate prediction of weather phenomena and understanding the phenomena are important. Learn the basis of radar observation by visiting radar observation station and having lectures. Students will also obtain a skill to analyze radar data by developing programs.
Participatory self-build place making to nurture sense of belonging
By using elementary school left over rooms in useful and inovative way of using the space, we would like to propose new ways of living and revitalizing the area.
Participatory self-build place making to nurture sense of belonging
By using bamboo which has been abondoned and become harmful to the broad leaved forest in useful and intimate way to people, we would like to propose new ways of using the material, bamboo, and of revitalize the area.
algorithmic design
Re-design design proposals designed using analog methods in the design studios and other design studios that have been taken in the past using algorithmic design methods.
Dessication resistance of terrestrial cyanobacterium
Experiments on the viability of terrestrial cyanobacteria against dry heat will be conducted to elucidate the mechanism of thermal tolerance of terrestrial cyanobacteria.
Reconstruction of Biochemical Networks based on Trans-Omics analysis
Survey previous papers and analysis data to discuss datasets and methods used in analyses that integrate GWAS and transomics. Prepare for analysis using glial cell data. Learn transomics analysis methods by following up on experiments and analyses conducted by the instructor. In addition, practice programming (Python, R) and develop skills for data analysis and software development.
Biological survey of Shonai area
Field surveys and sampling in the Shonai area will be conducted to identify species by morphological and DNA barcoding. During the Natsu-pro, we will organize information on the habitat of myxomycetes and spiders in particular.
The Psychology of Perception and Cognition
This Special Research Project B aims to acquire the outstanding skills necessary to explore the perception science of spatial and textural information. In particular, we will focus on developing practical skills and understanding the fundamentals of psychophysical measurement methods and mathematical psychology. We will deal with perceptual and cognitive phenomena such as space perception, shitsukan perception, self-motion perception, visual information processing, perception and motion, and memory. We will touch on mathematical model construction and mathematical models using differential equations and linear algebra.