Why does scientific advice on nutrition keep changing? Does hydroxychloroquine cure coronavirus? How can we tell the difference between a scientific breakthrough and fake news? And how can a budding scientist do exciting research that will save the world and land you a job without following in the footsteps of the fraudsters and spin artists who have been taken down by scientific scandals? This course will look closely at some of the worst examples of science gone wrong from across all disciplines, including RIKEN’s faked stem cell images, the over-hyped “Mozart effect”, scientific racism in IQ and skull measurements, and Excel errors in GDP:debt ratio calculations. Taught by someone with first-hand experience both with using open science and with retracting a high-profile journal article, we will have frank discussions about the perverse incentives that select for unethical science practices and how we might fix them.