In this lecture, students who have never conducted molecular biology experiments will be explained from the handling of laboratory equipment so that they can start research smoothly. In addition to simply explaining the experimental methods, I will also lecture my own research experiences and failures. Originally, research is to acquire actual knowledge and skills by being scolded by faculty members and seniors in the laboratory, and it takes a long time. In my domestic and international research life, there was no class to transfer systematic techniques and know-how, and I have never heard of such a story. Therefore, many students are making similar mistakes. In this class, I will make use of such experiences, incorporate my own research experiences and failures, and generously convey information useful for efficient research of students.