
Screening for genes determining the sensitivity to anticancer drugs using open database
Drug therapy is one of the major therapeutic methods in cancer treatment. While various anticancer drugs have been developed, we always confront the issues of drug refractory or acquired drug resistance. Hence, it is warranted to discover biomarkers that can predict the effect of drugs in advance. In this project, we will search for genes which expression levels correlate with the sensitivity to anticancer drugs using cancer cell line databases.
Students will learn how to use cancer cell line database (CellMinerCDB and others). Through these analyses, students will learn how anti-cancer agents act, and about DNA repair.