
14717 items found.
Urban Fabrication Lab (Machi-Mono-Tsukuri)
In accordance with the Comprehensive Agreement on Creative Future Cities (2020) between the SFC Research Institute and Kamakura City, this project will be implemented in Kamakura City, where students will learn how to creatively solve the issues faced by local governments. This term, we will research small parks dotted around Kamakura City, propose new ways to use them that fit the times, and create prototypes using 3D printers and recycled materials to chart a path to future park revitalization. explore.
Together with Erika Nakagawa, this research group aims to invent and discover new architecture.
Based on the theme of living preservation of private houses in the city, students will explore the existing conditions of the site, learn about independent construction methods, experience the effects on-site, and discuss them.
In this term's special project A, participants will work with professional builders to construct a frame that is an applied version of traditional wooden construction methods, allowing them to experience architectural mechanics from the perspective of the building in front of them.
The aim is to gain learning from on-site lectures and exercises that cannot be obtained from university lectures.
In Search of Future of Organizations
We will collaborate with Iki City in Nagasaki Prefecture to conduct joint research and practice on organizational engagement and transformation. By analyzing data from an engagement survey conducted by Iki City from the perspective of the course participants, we will provide recommendations on future work styles and organizational structures. Additionally, we will conduct interviews with Iki City employees on-site and formulate further recommendations based on the insights gained from these interviews.
Understanding of the metabolome analysis methods
Recently, various types of metabolome analysis methods have appeared, and it is possible to measure a large number of metabolites. In this project, we will deepen our understanding of typical metabolome analysis methods and conduct metabolome analysis research using actual instrument.
Molecular mechanisms controlling early development
In the Wet-Bio building located in the SFC, various experiments such as gene introduction, microscopic observation of organisms, and breeding of small aquatic organisms are possible. Participants will be those who are usually interested in the life phenomena of a particular organism. First, each person shares their research content as a whole, then discusses the questions and solutions, and then discusses what could be considered if a survey were conducted based on that premise. Each person will follow suit, make a detailed plan for conducting the experiment, and announce the progress.
Practicing and Reviewing Oral history
Since 2009, SFC Oral History Study Group has had the opportunity to deepen its understanding beyond the semester-long classroom seminar by conducting fieldwork and presenting research on the practice of listening. With sufficient prior research, the aim is to get a sense of life, society and history in the field and to contribute to the development of their own research and projects.
Fieldwork of Japanese politics and diplomacy
Since 2007, SFC Japanese Politics and Diplomacy Seminar has been continuing had the opportunity to visit sites of Japanese political diplomacy (history) to conduct fieldwork and present research, thereby deepening understanding beyond the semester-long classroom seminars. With sufficient prior research, the aim is to get a sense of politics, diplomacy and history in the field, and to contribute to the development of their own research and projects.
Molecular mechanisms controlling early development
In the Wet-Bio building located in the SFC, various experiments such as gene introduction, microscopic observation of organisms, and breeding of small aquatic organisms are possible. Participants will be those who are usually interested in the life phenomena of a particular organism. First, each person shares their research content as a whole, then discusses the questions and solutions, and then discusses what could be considered if a survey were conducted based on that premise. Each person will follow suit, make a detailed plan for conducting the experiment, and announce the progress.
Do-It-Anyway
Experiences in architectural and urban design education on the East Coast of the U. S., as well as visits to architectural renovation sites and workshops to experience space creation.
Study on Functional RNAs
Since the end of the last century, the complete genomic sequences of many organisms have been determined. The impact of these genome projects on the various fields of science has been enormous. It could be said that we now have in our hands “the blueprints of life” for these organisms. At the beginning of the 21st century, it became apparent that large numbers of noncoding RNAs are, unexpectedly, encoded in these genomes. These RNAs are not translated into proteins but act as riboregulators, and have had another huge impact on the life sciences. More recently still, a new tide of research into the classical noncoding RNAs, such as the transfer RNAs (tRNAs), has arrived. In this project, we are especially focusing on the following subjects: (1) Construction of an expression system on microbial membranes for peptides that capture microplastics. (2) Research on the origin of the Ebola virus. (3) Analysis of CSD protein(s) possibly involved in transcription elongation and termination. (4) Identification of microorganisms in specific rocks..
Study on Functional RNAs
Since the end of the last century, the complete genomic sequences of many organisms have been determined. The impact of these genome projects on the various fields of science has been enormous. It could be said that we now have in our hands “the blueprints of life” for these organisms. At the beginning of the 21st century, it became apparent that large numbers of noncoding RNAs are, unexpectedly, encoded in these genomes. These RNAs are not translated into proteins but act as riboregulators, and have had another huge impact on the life sciences. More recently still, a new tide of research into the classical noncoding RNAs, such as the transfer RNAs (tRNAs), has arrived. In this project, we are especially focusing on the following subjects: (1) Analysis of the nucleic acid binding ability of CSPs involved in transcription elongation and termination processes. (2) 16S rRNA amplicon analysis of bacterial communities colonized on pegmatites.
Novel Urban Element Design with 3D Printing
For the research presentations at the Conference on 4D and Functional Fabrication 2023 (https://sig4dff.org/conference/2023/) to be held on 11/1 and 11/2, and for the associated social experiments, students will practice actually producing "urban elements" using a large-scale composite-type 3D printer. Depending on the prepared fabrication equipments, the workshop will be held at SFC, Kamakura Lab, and other studios in the cities, with the expectation that the all production works will be connected through on-line classes (meetings).
Translated with www.DeepL.com/Translator (free version)
Measurement and analysis of neural information
A recent advance in noninvasive brain measurement techniques has enabled us to see human brain functions. In kenkyukai, we have learned these techniques as well as analysis methods, but less attempts have been made to survey background studies and summarize the knowledge. Therefore, we will prepare for the project by surveying neural information studies and by submitting the survey content as a preliminary assignment (please submit it by the end of January 2023). In this project, we will first survey neural information studies for summarization. Then, we will summarize the survey content and present it each other. Finally, we will share and structuralize the summarized content, and upload it on the web as a final assignment (please submit it by the end of February, 2023).
We will examine and practice what measures should be taken to mitigate damage in response to disasters such as the coming earthquake directly under the Tokyo metropolitan area, the Nankai Trough, and the Kuril Islands Trench. We will consider scientific, educational, social, and informational approaches, without ending with theory or practical drinking, and summarize them as materials that can be used by the people who are expected to be involved.
Novel Urban Element Design with 3D Printing
For the research presentations at the Conference on 4D and Functional Fabrication 2024 (https://sig4dff.org/conference/2024/) to be held on 10/24 and 25, and for the associated social experiments, students will practice actually producing "urban elements" using a large-scale composite-type 3D printer. Depending on the prepared fabrication equipments, the workshop will be held at SFC, Kamakura Lab, and other studios in the cities, with the expectation that the all production works will be connected through on-line classes (meetings).
Translated with www.DeepL.com/Translator (free version)
Study on Functional RNAs
Since the end of the last century, the complete genomic sequences of many organisms have been determined. The impact of these genome projects on the various fields of science has been enormous. It could be said that we now have in our hands “the blueprints of life” for these organisms. At the beginning of the 21st century, it became apparent that large numbers of noncoding RNAs are, unexpectedly, encoded in these genomes. These RNAs are not translated into proteins but act as riboregulators, and have had another huge impact on the life sciences. More recently still, a new tide of research into the classical noncoding RNAs, such as the transfer RNAs (tRNAs), has arrived. In this project, we are especially focusing on the following subjects: (1) Construction of a biofilm-producing system by inducing the expression of specific gene(s). (2) Evolutionary analysis of VP35 proteins in Filoviridae. (3) Analysis of CSD protein(s) possibly involved in transcription elongation and termination.
Systems Biology
"Life" was once thought to be so complex that it would be impossible to understand its entirety. However, with the advent of the 21st century, it has become possible to analyze large amounts of biological information, including genomes, and with the use of information technology, it is no longer a dream to understand the full extent of "life". SFC has been a pioneer in this field for more than two decades.
The applied fields of systems biology are unlimited, ranging from medical science, environmental science and ecology, food science, to the elucidation of the origin and evolution of life. In this special research project, we will conduct intensive research on a specific theme within the scope of advanced biosciences.
Systems Biology
"Life" was once thought to be so complex that it would be impossible to understand its entirety. However, with the advent of the 21st century, it has become possible to analyze large amounts of biological information, including genomes, and with the use of information technology, it is no longer a dream to understand the full extent of "life". SFC has been a pioneer in this field for more than two decades.
The applied fields of systems biology are unlimited, ranging from medical science, environmental science and ecology, food science, to the elucidation of the origin and evolution of life. In this special research project, we will conduct intensive research on a specific theme within the scope of advanced biosciences.
Multi-omics analysis of microorganisms on the human body.
It is known that there are about 40 trillion microorganisms of about 1,000 species living symbiotically in the human body. These flora vary greatly depending on the individual and the environment, and are known to have various effects on the human body through crosstalk with the host. In this project, we focus on intestinal bacteria and skin indigenous bacteria among the indigenous bacteria in the human body, and analyze the bacterial flora by meta-16S rRNA gene sequencing and metabolome analysis using CE-TOFMS to clarify the interrelationship among bacterial flora, metabolites, and host. In this spring project, we will conduct bacterial flora analysis and metabolome analysis, and discuss among the members to develop our individual research.
Synthetic biology
This project aims to establish the methodologies necessary to elucidate the natural transforming ability of Bacillus subtilis, the structure of spider webs and web-making behavior, and the relationship between the growth of Myxomycetes and the surrounding microorganisms, which are attracting attention as biological functions.
SFC kotan: Learning the Aynu Language and Oral Literature
This project is intended for students who are already studying the Aynu language and culture. We will visit the important places engaged in the revitalisation of Aynu language and culture.
Function and structural analysis of polyketide synthases
Modular polyketide synthase (PKSs) synthesize the core structures of diverse natural products, including antibiotics and immunosuppressants. However, since modular PKSs are huge enzyme, their entire protein structures have not yet determined. Here, by first predicting the structure of the protein using AlphaFold2, we will confirm how the structural difference occurs in all PKSs whose three-dimensional structure has been determined. In addition, we will analyze the expression and function of proteins that visualize the structure.
Genetic engineering in cancer research
Learn about the analysis methods used in cancer research and build a foundation for advanced experiments, including the latest genetic manipulation using CRISPR Cas9.
Learn about basic techniques such as cell culture, PCR and western blotting, and advanced experimental techniques such as flow cytometry and manipulation of viruses in the CRISPR Cas9 system.
With the advent of high-throughput sequencing technologies, comprehensive molecular studies of non-classical model organisms are becoming increasingly feasible. To this end, in this research project, we study non-classical model organisms such as spiders, tardigrades, ants, and etc. using comprehensive omics approaches, and by analyzing the resulting big data with bioinformatics, to elucidate their unique biology.
This project employs either or both of wet and dry approaches. Experimental biology part includes RNA extraction from the non-classical model organisms and sequencing with high-throughput sequencers. Bioinformatic part includes software development and analysis for the omics data.
Interdisciplinary RNA research
RNA controls higher-order biological phenomena in a complex and precise manner. In this spring project, we will investigate how RNA and related biomolecules contribute to our respective research themes through experiments with both living organisms and computers, with the aim of deepening our understanding of life phenomena.
Specifically, we will conduct research on the regulation of gene groups or gene expression in various environments in Halomonas species, the development of artificial cells as biosensors, and the in vitro synthesis of long RNAs with hyper-repetitive sequences.